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Thursday, August 13, 2009

Maitake Extract Research Summary

By Dr. Markho Rafael

A culinary delicacy as well as an important medicinal mushroom in Traditional Chinese Medicine, Maitake currently receives much attention from scientific circles. Specific focus is awarded to Maitake beta-glucans, which are major components in all Maitake extracts. [71, 72]

The common English name for Maitake is Hen-of-the-woods, due to its occasional resemblance to the fluffed up tail feathers of a hen. It is one of the most easily recognizable edible mushrooms in North America, though it is only to be found in eastern Canada and U.S. down to the Mid-Atlantic States.

Scientific research on Maitake extract has found that it increases the tumor necrosis factor [73, 74, 75] and enhances other anti-cancer mechanisms. [76, 77, 78, 79, 80, 81] Specific cancer types studied include prostate, breast, liver, lung and colorectal cancer. [82] A Phase II study of Maitake on prostate and breast cancer has been FDA approved. [83]

Other studies on Maitake extract have focused on its immune enhancing properties in general, [84, 85, 86] or on immune-enhancement on cancer patients in specific. [87] Maitake's anti-viral properties have received particularly intense scrutiny by the scientific community [88] and research on Maitake in the treatment of HIV is ongoing. [89]

Of further interest is the well demonstrated blood sugar lowering effect of Maitake extract. One study on insulin-resistance found blood glucose drops of 25% average. [90, 91, 92]

Additional research has also been conducted on beta-glucan polysaccharides as isolated compounds. There is a pending patent on "Methods of using beta glucan as a radio-protective agent," which "relates to methods for treating and preventing radiation and/or chemotherapy related injury and/or afflictions, such as myelosuppression and decreased macrophage activity," [93] In light of this, it should come as no surprise that NASA gives beta-glucans to its astronauts as protection against radiation poisoning and subsequent immune system degradation.

Many other effects of Maitake extract have been researched with promising results, including: blood pressure regulation, respiratory conditions, stress and nerve tonic, anti-bacterial and anti-Candida. [25]

Medicinal mushroom expert Paul Stamets, in his book Mycelium Running, also lists Maitake extract as showing some positive effect on leukemia. [134]

Note: The statements on this page have not been evaluated by the Food and Drug Administration. This article is not intended to diagnose, treat, cure or prevent any disease. Always consult a licensed medical practitioner before using any herb (or mushroom) for medicinal purposes.

Credits: Thank you, Paul Stamets, for research references. - 17274

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