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Sunday, July 19, 2009

Medicinal Mushroom Hot Water Extract vs. Alcohol Extract

By Dr. Markho Rafael

Medicinal mushrooms, hugely popular for thousands of years in the Orient, are coming in vogue today also in the West. On the coattails of their increasing popularity follow issues of quality and ethical representation between competing brands.

All medicinal mushroom species are plagued by this. Most fiercely debated is red reishi (Ganoderma lucidum), the most popular of all medicinal mushrooms. So this article will primarily focus on that species, but it's generally applicable to all species of medicinal mushrooms.

An obvious caution is to stay away from cheap, mass-produced reishi. It may be merely dried and pulverized. In order to be medicinal, the mushroom cell-wall has to be broken down. Mass-produced reishi may be mostly inert and ineffective.

Then there are the real therapeutic grade red reishi brands, which are produced with much more care. But even here there are big differences between brands. Each claims to be the best, of course, because they want to sell their product. So lets set the facts straight and be independently informed consumers.

Following are the three primary ways of creating reishi extracts. Each method yields different medicinal compounds, all of which are shown in scientific studies to have important properties.

1. Hot Water Extraction (polysaccharides, etc.)

2. Alcohol Extraction (triterpenoids, sterols)

3. Fermentation (arabinoxylanes, etc.)

Polysaccharides have been shown to possess powerful anti-tumor qualities through enhancing the immune system and by inhibiting blood profusion through tumors. They are also strong antioxidants. [1]

Triterpenoids include a large number of related medicinal compounds whose proven effects include stabilization of blood pressure, cholesterol, and blood clotting. But most importantly, the triterpenoids are the anti-inflammatory compounds of reishi. [1] Inflammation is a serious component in asthma, allergies, arthritis and many more conditions.

Finally, by fermenting the red reishi, the original medicinal compounds break down to form new compounds with unique healing properties. These "secondary metabolites" have among other things been shown to be immune enhancing and help regulate blood sugar, as well as having unique anti-tumor properties. [2]

Since this article is not intended to elevate any one brand over another, no brand names will be mentioned. Nevertheless, the author does know of two highly reputed brands (American and Japanese) that claim only hot water extracted red reishi is of any value and that alcohol extracts are useless.

Naturally, the reason they say so is because they want to sell their own brand. However, those statements are scientifically untrue. Hot water and alcohol extractions both contain critical compounds.

To determine if a brand of reishi (or Ganoderma) contains all the important medicinal compounds from the mushroom, find out if it utilizes both alcohol and hot water extraction. An additional plus would be if it also includes fermented reishi.

As a last point, when you look for the best reishi extract, one thing to look at is the form it comes in. For example, any reishi extract that fully dissolves in a water-based liquid such as coffee probably only contains hot water extracted reishi. So while reishi/ganoderma coffee certainly makes for a superbly delicious and healthy cup loaded with polysaccharides, it won't include the important anti-inflammatory triterpenoids.

Surprisingly, though, alcohol tinctures may include both hot water extract and alcohol extract. You will know if the alcohol tincture contains polysaccharides because when the alcohol and hot water extracts are blended, the polysaccharides fall out of solution and the tincture becomes cloudy. (Just shake it before you take it.) A cloudy medicinal mushroom tincture is an indication of high polysaccharide content. Capsules and tablets may be either hot water extract or alcohol extract or both.

[1] Boh B, Berovic M, Zhang J, Zhi-Bin L. "Ganoderma lucidum and its pharmaceutically active compounds." Biotechnol Annu Rev. 2007;13:265-301.

[2] Tang YJ, Zhang W, Zhong JJ, 2009. "Performance analyses of a pH-shift and DOT-shift integrated fed-batch fermentation process for the production of ganoderic acid and Ganoderma polysaccharides by medicinal mushroom Ganoderma lucidum." Bioresource Technol. Mar;100(5):1852-9. - 17274

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