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Tuesday, September 29, 2009

Introducing: The Immune Booster - Colostrum

By Dr. Anthony Kleinsmith

The Immune Factors.

To comprehend what the Immune Factors are in high quality first milking colostrum and what they do, it is important to recognize that some of these components have one or more effects on the overall regulation and functioning of the immune system (immuno-regulating substances), while others are very restricted in what they can do and their benefits are usually very localized in the body, ordinarily exerting their effects primarily in the gut (gut protective substances).

Let's meet the Immuno-Regulating Substances

Thymosin (Alpha and Beta Chains) - This hormone has two protein-based chains which are present separately in colostrum. These chains either act together to activate, develop and maintain the immune system, or they act independently on the thymus gland.

Proline-Rich Peptide (PRP) - This small protein acts like a hormone as it works on the thymus and other immune system organs. It keeps these organs from over-reacting to an insult. It is also called Thymulin.

Cytokines. Small proteins produced by various cells in the body that induce the generation of specialized types of white blood cells, signal them to come to the site of an insult and help in their passage through tissues.

Lymphokines. Proteins of varying sizes that are produced by different types of white blood cells that tell related cells to transform themselves into more functional cell types that can release substances capable of destroying an invading microorganism.

Gut Protective Substances

Immunoglobulins (IgG, IgM, IgA) - These are complex proteins which are also called antibodies. These proteins are a significant portion of proteins found in colostrum. A mother cow's immune system produces these antibodies throughout her life as she responds to multiple different microorganisms. These proteins are then transferred prior to parturition into the colostrum. These antibodies react against fungi, viruses and bacteria that attack the gastrointestinal tract in humans.

Transfer Factors - Some certain types of microorganisms reside in the deep tissues of a body for a long period of time; when a body is exposed to these specific microorganisms, then transfer factors are produced to respond. They are small proteins and their area of expertise is to work together with different white blood cells and other factors to help keep microorganisms from infecting the body.

Lactoferrin. A mineral-binding carrier protein that attaches to available iron. Certain aerobic bacteria, like E. coli, require iron to reproduce and, therefore, lactoferrin is an effective substance, when operating in the presence of a specific antibody, to impede the growth of some microorganisms in the gut. A broad number of additional claims have been made by some providers of colostrum for human consumption regarding the application of lactoferrin as an immuno-regulating substance with antiviral, antibacterial and anti-tumor properties. To date, none of these claims have been adequately substantiated through properly controlled studies.

Transferrin - This mineral-binding carrier protein also attaches to iron that is available. It can either act together with Lactoferrin or on its own to impede the growth of microorganisms in the gut.

Lysozyme - This enzyme attaches itself to cell walls of pathogenic bacterias as well as degrading proteins. Once it attaches, it is very powerful because it leaves holes in the walls of the bacteria.

Lactoperoxidase - This enzyme also attaches itself to cell walls of bacterias and degrading proteins. Once it attaches, it is mildly effective as it interferes with the bacteria's replication.

Xanthine Oxidase - This mildly effective enzyme is similar in effect to Lactoperoxidase, because it can also attach itself and interfere with the replication of different degrading proteins and bacteria than Lactoperoxidase.

White blood cells (leukocytes). Primarily three types of functional white blood cells are present in colostrum, including neutrophils, macrophages and polymorphonuclear cells. Each has the ability to phagocytize microorganisms and other foreign bodies and apply substances carried internally to the destruction of the microorganisms. Their functions are dramatically enhanced when antibodies first attach to the microorganisms.

Oligosaccharides and glycoconjugates. Complex carbohydrates (sugars) that can adhere to specific sites on the inner surface of the gastrointestinal tract and prevent the attachment of microorganisms. - 17274

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